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为探讨老年急性心肌梗死(AMI) 患者静脉溶栓前后QT 离散度(QTd) 变化及对预后的影响,对77 例老年AMI患者分为溶栓再通组、未通组和非溶栓组,测定其溶栓前及溶栓治疗2 周后QTd 变化,并与非溶栓组比较,同时比较三组治疗2 周时高危室性心律失常。结果发现溶栓治疗再通后QTd 显著减小,高危室性心律失常的发生率低,其与未通组及非溶栓组比较,差异有显著性( P< 0-01),而未通组、非溶栓组治疗前后QTd 变化不显著且二者比较差异无显著性( P>0-05) ;QTd 增大者,发生高危室性心律失常的比率增大。说明老年AMI患者静脉溶栓治疗再通后,随心肌缺血改善,QTd 减小,高危室性心律失常发生率低;而溶栓未通组和非溶栓组QTd 增大者其高危室性心律失常的发生率增高。
To investigate the changes of QTd before and after intravenous thrombolysis in elderly patients with acute myocardial infarction (AMI) and its effect on prognosis, 77 elderly AMI patients were divided into thrombolytic group, untreated group and non-thrombolytic group, The change of QTd before thrombolytic therapy and 2 weeks after thrombolytic therapy were measured. Compared with non-thrombolysis group, the high-risk ventricular arrhythmias were also compared in two groups at the same time. The results showed that the thrombolytic therapy recanalization after QTd significantly reduced the incidence of high-risk ventricular arrhythmias, its non-and non-thrombolytic group, the difference was significant (P <0-01), and did not pass There was no significant difference in QTd between the two groups before and after treatment (P> 0-05). The higher the QTd, the higher the incidence of high risk ventricular arrhythmias. The results showed that the improvement of myocardial ischemia, QTd decreased and the incidence of high-risk ventricular arrhythmias were lower in elderly patients with AMI after recanalization by intravenous thrombolysis. However, the high-risk ventricular The incidence of arrhythmia increased.