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目的探讨降钙素原(PCT)在新生儿重症感染时的诊断价值。方法将167例住院新生儿分严重感染组、一般感染组、非感染组、恢复期组4组,检测血清PCT、血清CRP、白细胞计数及分类,进行结果分析。结果以PCT≥0·5ng/ml为阳性,各组阳性:重感染组为88·00%,一般感染组为55·00%,非感染组为14·29%,恢复期组为9·52%,严感染组阳性率明显高于其他3组与3组间两两比较,差异有统计学意义(Hc=73·24,P<0·00)。结论PCT可作为新生儿感染的早期检测指标,动态检测PCT可判断疗效及预后。
Objective To investigate the diagnostic value of procalcitonin (PCT) in severe neonatal infections. Methods A total of 167 hospitalized neonates were divided into four groups: severe infection group, general infection group, non-infected group and convalescent group. The serum PCT, serum CRP, leukocyte count and classification were analyzed. The results were positive with PCT≥0.5 ng / ml. The positive rates were 88.00% in the severe infection group, 55.00% in the general infection group, 14.29% in the non-infected group and 9.22 in the recovery group %, The positive rate of infected group was significantly higher than the other three groups and any comparison between the three groups, the difference was statistically significant (Hc = 73 · 24, P <0 · 00). Conclusion PCT can be used as an early detection index of neonatal infection, dynamic detection of PCT can determine the efficacy and prognosis.