1病例介绍患者女,61岁。因“间断性呕吐30余年,加重伴胸骨后、背部疼痛3个月”入院。检查:①食管造影:纵隔明显增宽,食管明显扩张,黏膜絮乱,约胸3、4椎体平面食管右侧壁见大小5.2cm×6.9cm的充盈缺损,局部食管黏膜破坏;贲门张力高,食管内容物潴留明显,考虑贲门失弛缓症合并食管癌(图1)。②胃镜:食管距门齿20～27cm见一巨大溃疡性新生物,局部 1 case description Female patient, 61 years old. Because of “intermittent vomiting for more than 30 years, increased with the sternum, back pain for 3 months ” admission. Check: ① esophageal angiography: mediastinum was significantly widened, esophageal significant expansion, mucosal flocs, about chest 3,4 vertebral plane esophageal right side see the size of 5.2cm × 6.9cm filling defect, partial esophageal mucosal damage; high cardiac tension , Esophageal retention was obvious, consider achalasia with esophageal cancer (Figure 1). ② endoscopy: esophageal incisors 20 to 27cm to see a huge ulcer of new biological, local