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目的探讨采用四联疗法临床治疗胆汁反流性胃炎的疗效分析。方法本文将回顾分析2009年5月至2011年9月间我院收治的136例胆汁反流性胃炎患者,并随机将其分治疗组和对照组,其中治疗组采用四联疗法(雷贝拉唑、莫沙比利、硫糖铝混悬剂、铝碳酸镁咀嚼片),对照组采用常规的普通治疗法。结果治疗组的总有效率为95.59%,而对照组总有效率69.12%;在停药后6个月随访中部分患者出现复发,其中治疗组有8例,复发率占总有效率的12.31%,而对照组有12例,复发率占总有效率的25.53%。结论通过本文的临床实践显示,采用四联疗法(即:雷贝拉唑、莫沙比利、硫糖铝混悬剂、铝碳酸镁咀嚼片)治疗胆汁反流性胃炎,具有较好的临床疗效,且其不良反应较为轻微,因此值得临床推广与应用。
Objective To investigate the efficacy of quadruple therapy in the treatment of bile reflux gastritis. Methods This retrospective analysis of 136 cases of bile reflux gastritis admitted to our hospital from May 2009 to September 2011 was randomly divided into treatment group and control group. The treatment group was treated with quadruple therapy Azole, mosapride, sucralfate suspension, and aluminum magnesium carbonate chewable tablets), and the control group was treated with the conventional common therapy. Results The total effective rate in the treatment group was 95.59%, while the control group was 69.12%. In the follow-up 6 months after discontinuation, some patients showed recurrence, of which 8 cases in the treatment group, the recurrence rate accounted for 12.31% of the total effective rate , While the control group had 12 cases, the recurrence rate accounted for 25.53% of the total effective rate. Conclusion The clinical practice of this study shows that the use of quadruple therapy (ie, rabeprazole, mosapride, sucralfate suspension, aluminum magnesium carbonate chewable tablets) treatment of bile reflux gastritis, has a good clinical Efficacy, and its adverse reactions are minor, it is worth clinical promotion and application.