氧氟沙星具有广谱、高效杀菌作用 ,特别是对革兰氏阴性及阳性菌有强抗菌作用 ,被广泛应用于临床。在临床用药中发生不良反应较少。我院曾遇到一例氧氟沙星注射液与微量碳酸氢钠所引起的不良反应。1　病例报告患者 ,男 ,6 8岁 ,诊断为胆囊炎。住院后给静脉点滴 5 %碳酸氢钠 2 0 Ofloxacin has a broad spectrum, efficient bactericidal effect, especially against Gram-negative and positive bacteria have strong antibacterial activity, is widely used in clinical. Adverse reactions in clinical medication less. Our hospital had encountered a case of ofloxacin injection and trace sodium bicarbonate caused by adverse reactions. 1 case report patients, male, 6 8 years old, diagnosed as cholecystitis. After hospitalization intravenous drip 5% sodium bicarbonate 20