晚发性维生素K缺乏,又称婴儿获得性凝血酶原复合因子缺乏症,伴颅内出血者占80%。1966年首先由Goldman等报告,称为新生儿期后凝血酶元低下症。本症在临床并不少见,发病急,病情重,病死率和病残率高。但诊断并不困难,早期治疗效果好。关键是提高认识,及时诊断。本文对我院1981年至1987年收治的11例作一报道。 Late onset vitamin K deficiency, also known as infant acquired prothrombin factor deficiency, with intracranial hemorrhage accounted for 80%. First reported in 1966 by Goldman et al., Referred to as hypothyroidism after neonatal period. This disease is not uncommon in clinical, acute onset, severe illness, case fatality and morbidity. But the diagnosis is not difficult, early treatment is effective. The key is to raise awareness and diagnose in time. This article from 1981 to 1987 in our hospital for 11 cases made a report.