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目的:探讨代谢综合征(MS)与勃起功能障碍(ED)和睾酮(T)的关系。方法152名被调查者被列入本研究。病人全部填写国际勃起功能指数(IIEF-5)问卷。代谢综合征的诊断标准根据2005年国际糖尿病联盟颁布的国际学术界第一个MS的全球统一定义,该定义明确以中心性肥胖为核心。腰围作为中心性肥胖的诊断指标。探讨代谢综合征对男性勃起功能和睾酮的影响。结果42名被调查者构成了代谢综合征组,代谢综合征患者IIEF-5评分分别为(16.67±4.00)分和(19.16±6.32)分,两者比较,差异具统计学意义(P<0.05)。血清睾酮分别为(4.18±1.55)ng/ml和(6.06±3.04)ng/ml,两者比较,差异具统计学意义(P<0.01)。血清睾酮中心性肥胖者明显低于非中心性肥胖者,两者比较差异具统计学意义(P<0.01)。结论代谢综合征是ED和影响睾丸分泌的潜在风险因素。在代谢综合征患者诊断中应询问ED病史,腰围测量可作为ED评价的一部分。“,”Objective To investigate the relationship between metabolic syndrome and erectile dysfunction, as well as serum testosterone level. Methods Total of 152 patients, who completed International Index of Erectile Function (IIEF-5) questionnaire,were recruited in the study. Patients with metabolic syndrome was diagnosed as the global criterion, which was published by International Diabetes Federation in 2005. The core of this criterion was central obesity, which was mainly determined by waist circumference. Results The IIEF-5 score and serum testosterone level of patients in the metabolic syndrome group, (42) were 16.67±4.00 and 4.18±1.55 ng/ml respectively, and those of patients in the non-metabolic syndrome group were 19.16±6.32 (P<0.05) and 6.06±3.04ng/ml (P<0.01)respectively. The serum testosterone level of patients in the central obesity group was significantly lower than that of the non-central obesity group (P<0.01). Conclusion Metabolic syndrome was a potential risk factor to induce erectile dysfunction and influence the secretion of testosterone. Patients with metabolic syndrome should be asked the ED history, and their waist circumference could be one of ED evaluation parameters.