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20例难治性室早患者分别经心律平、慢心律、胺碘酮、妥卡律治疗无效,改用慢心律与心律平联合治疗后获满意效果,现报道如下。材料与方法20例中男7例,女13例,均为本院住院病人,年龄24～48岁。病毒性心肌炎后8例,高血压病4例,原发性扩张型心肌病2例,不明原因者6例。入院前分别服用过心律平、慢心律、胺碘酮及妥卡律2～4周不等。入院后至少停药48小时或5个半衰期。然后进行24小时动态心电图(DCG)监测。20例均为频发室早,其中多源或成对室早10例,伴短阵室速5例;单纯频发室早10例,伴短阵室速2例。
Twenty patients with refractory ventricular asymptomatic patients were treated with amiodarone and Tacrolimus respectively by heart rate, slow heartbeat rate, and satisfactory results after switch to slow heart rate and cardiac rhythm. The results are reported as follows. Materials and Methods 20 males and 7 females, 13 females, all hospitalized patients, aged 24 to 48 years old. 8 cases of viral myocarditis, 4 cases of hypertension, 2 cases of primary dilated cardiomyopathy, 6 cases of unknown reasons. Before admission were taken heart rhythm, slow heart rate, amiodarone and Tolcaidine 2 to 4 weeks. At least 48 hours or 5 half-lives after admission. Then a 24-hour Holter Monitor (DCG) was performed. All of the 20 cases were frequent premature ventricular contractions. Among them, 10 cases were multi-source or paired as early as 5 cases accompanied with MPT; 10 cases were as early as simple frequency room with 2 cases with MPV.