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绒毛膜羊膜炎(chorioamnionitis,CAM)是指病原体感染胎盘的绒毛膜羊膜和蜕膜而形成的炎症。CAM是早产、胎膜早破及母儿感染的重要原因。多项研究表明[1-2],CAM可导致母儿不良妊娠结局。CAM分为临床绒毛膜羊膜炎和组织学绒毛膜羊膜炎(histologic chorioamnionitis,HCA)。随着对胎盘病理重视程度的提高,HCA的诊断率显著升高。本研究通过回顾分析148例HCA患者及同期226例非HCA患者的病例资料,旨在探讨发生HCA的危险因素及HCA对妊娠结局的影响,以期得到临床对HCA的重视。
Chorioamnionitis (CAM) refers to inflammation of the placental chorion amniotic and decidual cells caused by pathogens. CAM is an important cause of preterm birth, premature rupture of membranes and maternal and child infections. A number of studies have shown that [1-2], CAM can lead to adverse pregnancy outcome in pregnant women. CAM is divided into clinical chorioamnionitis and histological chorioamnionitis (HCA). With the increased emphasis on the pathology of the placenta, the diagnostic rate of HCA is significantly increased. In this study, retrospective analysis of 148 cases of HCA patients and 226 cases of non-HCA patients at the same period the case data to explore the risk of HCA and HCA impact on pregnancy outcome in order to get the clinical attention to HCA.