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目的观察新型鼻塞持续气道正压呼吸治疗新生儿呼吸衰竭的临床疗效和安全性。方法选取医院收治的64例新生儿呼吸衰竭患儿,随机分为对照组和观察组,每组32例。对照组采用常规呼吸治疗,观察组采用新型鼻塞持续气道正压呼吸治疗,观察2组患儿治疗24 h后血气分析情况(pH值、PaO_2、PaCO_2、SpO_2)及疗效。结果观察组治疗总有效率为96.87%,高于对照组的87.50%(P<0.05)。观察组患儿pH值、PaO_2、PaCO_2、SpO_2水平均优于对照组,差异有统计学意义(P均<0.05)。结论呼吸衰竭新生儿采用新型鼻塞持续气道正压呼吸治疗,可提高治疗有效率,恢复正常呼吸功能,使血气指标能更快恢复至正常水平。
Objective To observe the clinical efficacy and safety of a new type of nasal continuous positive airway pressure in the treatment of neonatal respiratory failure. Methods Sixty-four neonates with respiratory failure were selected and randomly divided into control group and observation group, 32 cases in each group. The patients in the control group were treated with conventional respiration, and the patients in the observation group were treated with positive nasal continuous positive airway pressure. The blood gas analysis (pH value, PaO 2, PaCO 2, SpO 2) and the curative effect were observed 24 h after treatment. Results The total effective rate of the observation group was 96.87%, which was higher than that of the control group (87.50%, P <0.05). The pH, PaO_2, PaCO_2 and SpO_2 levels in observation group were better than those in control group, with significant difference (P <0.05). Conclusion Neonatal respiratory failure with a new type of continuous positive airway pressure treatment of nasal obstruction can improve the treatment efficiency and restore normal respiratory function, blood gas index can be restored to normal levels faster.