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目的探讨儿童炎性肌纤维母细胞瘤的CT表现。资料与方法回顾性分析6例经手术证实的炎性肌纤维母细胞瘤,将CT表现与手术病理结果相对照,所有病例均行CT平扫和增强。结果发生于大网膜和小肠系膜各1例,右侧卵巢系膜1例,乙状结肠系膜2例,右上肺1例合并支气管囊肿。CT表现实性肿块2例,3例表现为囊实性肿块,1例完全囊性。钙化4例,3例呈大片状,1例呈条状钙化。增强扫描肿瘤实性部分呈明显强化2例,病理上肿瘤血管异常丰富,1例后方见增粗的血管,3例分房状肿瘤间隔有强化,而中心成分无强化区病理上往往是黏液变性,未见肿瘤包埋血管。病理上瘤组织大部分由梭形纤维细胞构成,可有黏液变性和坏死、钙化。黏液/血管型3例,梭形细胞型1例,纤维型2例。5例免疫组织化学检查,4例波形蛋白(Vimentin)染色和平滑肌肌动蛋白(SMA)染色均呈阳性。结论 CT检查对炎性肌纤维母细胞瘤诊断能提供有价值信息。
Objective To investigate the CT findings of inflammatory myofibroblastic tumor in children. Materials and Methods Retrospective analysis of 6 cases of inflammatory myofibroblastoma confirmed by surgery, CT findings and surgical pathology results, all cases underwent CT scan and enhanced. The results occurred in the omental and small intestinal mesentery in 1 case, the right ovarian mesangial in 1 case, sigmoid mesangial in 2 cases, 1 case of right upper lung with bronchial cyst. CT showed solid mass in 2 cases, 3 cases showed cystic mass, 1 case of complete cystic. 4 cases of calcification, 3 cases were large, 1 was strip calcification. The enhancement of the solid part of the tumor was significantly enhanced in 2 cases, the pathological tumor vascular abnormalities rich, 1 case of see the thickening of the blood vessels, 3 cases of subtotal tumor interval enhanced, while the central component of the non-strengthening area is often pathological mucoid degeneration , No tumor-embedded blood vessels. Most of the pathological tumor tissue composed of spindle fibroblasts, mucus may have degeneration and necrosis, calcification. Mucus / vascular type in 3 cases, spindle cell type in 1 case, fibro type in 2 cases. Immunohistochemistry was performed in 5 cases, and 4 cases were positive for vimentin staining and smooth muscle actin (SMA) staining. Conclusion CT examination can provide valuable information for the diagnosis of inflammatory myofibroblastoma.