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多腺体自身免疫综合征为以一种内分泌腺功能障碍为主,而同时并有其它内分泌或非分泌器官自身免疫疾患的综合征。临床分为3型:PAS I型以甲状旁腺功能低下为主;Ⅱ型以阿迪森氏病为主,Ⅲ型以自身免疫性甲状腺炎为主病。PAS合并非内分泌器官病变目增。淋巴细胞浸润为其主要病理变化。本文报告PASⅢ型10例。2病并发者5例;3病并发者5例。经强地松及/或甲状腺片治疗后均缓解。
The polyglandular autoimmune syndrome is a syndrome characterized by an endocrine gland dysfunction while at the same time having other autoimmune disorders of the endocrine or non-secreting organ. Clinically divided into 3 types: PAS I-type hypoparathyroidism-based; Type II to Addison’s disease-based, type III to autoimmune thyroiditis-based disease. PAS merger non-endocrine organ lesions increased. Lymphocyte infiltration is the main pathological change. This article reports PAS Ⅲ type 10 cases. 2 cases of complicated by 5 cases; 3 cases complicated by 5 cases. After the strong pine and / or thyroid tablets were relieved after treatment.