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一般认为,西米替丁对实验动物和人的免疫增强,与逆转组胺H_2受体调节的免疫抑制有关。本文报道,ranitidine 对小鼠用SRBC 引起的迟发性超敏反应(DTH)的影响,并与西米替丁作比较。实验用12周龄的BALB/C 小鼠,皮下注射0.4ml
It is generally believed that the immunological enhancement of cimetidine on experimental animals and humans is related to the reversal of histamine H 2 receptor-mediated immunosuppression. This article reports the effect of ranitidine on delayed hypersensitivity (DTH) induced by SRBC in mice and compared with cimetidine. Experimental 12-week-old BALB / C mice were injected subcutaneously with 0.4 ml