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目的探讨高血压脑出血患者早期降压治疗对血肿扩大的影响。方法将91例入院时血压>180/110mmHg的高血压脑出血患者随机分为强化降压组和标准降压组,分别给予强化降压和标准降压治疗。观察24h后两组患者血肿体积的变化情况。结果强化降压组24h内血肿扩大者3例,占6.38%(3/47);标准降压组24h内血肿扩大者8例,占18.18%(8/44)。两组血肿扩大发生率比较,差异有统计学意义(P<0.05)。结论早期强化降压治疗高血压脑出血,可减少血肿体积进展,起到脑细胞保护作用,同时能改善神经功能。
Objective To investigate the effect of early antihypertensive therapy on hematoma enlargement in patients with hypertensive intracerebral hemorrhage. Methods 91 patients with hypertensive intracerebral hemorrhage> 180 / 110mmHg on admission were randomly divided into intensive antihypertensive group and standard antihypertensive group, and were given intensive antihypertensive and standard antihypertensive treatment respectively. The changes of hematoma volume in two groups were observed 24 hours later. Results 3 cases (6.38%) (3/47) had enhancement of hematoma enlargement in antihypertensive group within 24h, and 8 cases (18.18%) in standard antihypertensive group within 24 hours. The incidence of hematoma enlargement between the two groups, the difference was statistically significant (P <0.05). Conclusions Early intensive antihypertensive treatment of hypertensive intracerebral hemorrhage can reduce the volume of hematoma, play a protective role of brain cells, while improving neurological function.