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在生物体内既有产生自由基的体系,又有清除自由基体系;自由基既可给机体造成损害,机体也可利用自由基,其生成与清除必须保持平衡。一旦自由基的产生增多或机体清除自由基的能力减弱,则可造成对机体的损害,导致疾病。本文简要介绍生物体内自由基的产生、清除、利用和对细胞的损害。 自由基的共同特点是带有不成对的电子,如超氧化物自由基(O_2~-或HO_2)、氢自由基(H~.)、氢氧自由基(OH~-)等。生物体内的自由基主要
In the body of both existing free radical system, but also to eliminate the free radical system; free radicals can cause damage to the body, the body can also use free radicals, the formation and removal must be balanced. Once the increase in the production of free radicals or the body’s ability to scavenge free radicals, it can cause damage to the body, leading to disease. This article briefly introduces the generation, clearance, utilization and damage of free radicals in living organisms. Common features of free radicals with unpaired electrons, such as superoxide radicals (O_2 ~ - or HO_2), hydrogen free radicals (H ~.), Hydroxyl free radicals (OH ~ -) and so on. The main body of free radicals