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原发性肝癌是世界上最常见的恶性肿瘤之一，具有发病隐袭、病死率高的特点，早期诊断对预后的意义重大。单克隆抗体（ｍＡｂ）技术问世后，人们试图通过应用抗肝癌ｍＡｂ提高肝癌的早期诊断率。然而目前获得的抗肝癌ｍＡｂ识别的抗原都不是肝癌特异性抗原，而且由于肿瘤异质性
Primary liver cancer is one of the most common malignant tumors in the world, with the characteristics of insidious onset and high mortality. Early diagnosis is of great significance to prognosis. After the advent of monoclonal antibody (mAb) technology, people tried to improve the early diagnosis rate of liver cancer by using anti-liver cancer mAb. However, none of the antigens recognized by the anti-hepatoma mAbs currently obtained are liver cancer specific antigens, and due to tumor heterogeneity