论文部分内容阅读
对１５例常规治疗无缓解的重症阻塞性肺病患者进行纤维支气管镜吸痰和灌洗。吸痰和灌洗前、吸痰和灌洗后即刻和吸痰和灌洗后４小时测定肺功能〔时间肺活量第１秒率占预计值的百分比（ＦＥＶ１．０％）〕，吸痰和灌洗时监测血氧饱和度（ＳａＯ２）的变化。结果显示吸痰和灌洗后即刻ＦＥＶ１．０％无显著变化（Ｐ＞０．０５），吸痰和灌洗后４小时ＦＥＶ１．０％由０．４２±０．１２升至０．５７±０．１９，较前显著增高（Ｐ＜０．０１）。吸痰和灌洗时ＳａＯ２稍降低，但吸痰和灌洗后显著增高（Ｐ＜０．０５）。未发现严重的并发症。作者认为：纤维支气管镜吸痰和灌洗是重症慢性阻塞性肺病的有效治疗方法
Fifteen patients with severe obstructive pulmonary disease without remission were treated with bronchoscopy suction and lavage. Pulmonary function was measured before aspiration and as lavage, aspiration and immediately after lavage, and 4 hours after aspiration and lavage (percentage of first-second rate of time vital capacity (FEV 1.0%)], aspiration and irrigation Monitor changes in blood oxygen saturation (SaO2) during washout. The results showed that there was no significant change of FEV1.0% after sputum aspiration and lavage (P> 0.05). After suctioning and 4 hours after lavage FEV1.0% increased from 0.42 ± 0.12 to 0.57 ± 0.19, significantly higher than before (P <0.01). SaO2 slightly decreased during sputum aspiration and lavage, but increased significantly after sputum aspiration and lavage (P <0.05). No serious complications were found. The authors believe that: fiberoptic bronchoscopy suction and lavage effective treatment of severe chronic obstructive pulmonary disease