论文部分内容阅读
目的观察米索前列醇(米索)应用于高危妊娠分娩中预防产后出血的效果。方法选择124例有发生产后出血高危因素的产妇,随机分为米索组及对照组,各62例。米索组在胎儿娩出后立即日服米索前列醇400μg,对照组在胎儿娩出后立即肌注缩宫素20IU(缩宫素)。观察两组患者的第三产程时间、产后2h出血量、产后出血发生率的差异。结果两组相比,米索组较缩宫素组的第三产程时间平均缩短4min,产后2h出血量平均减少137mL,产后出血发生率平均低于对照组17%(P<0.01)。结论米索前列醇具有比缩宫素更强的缩宫作用,口服400ug就能很好地预防高危因素所致的产后出血。
Objective To observe the effect of misoprostol (misoprostol) in the prevention of postpartum hemorrhage during high-risk pregnancy delivery. Methods 124 cases of postpartum hemorrhage were selected risk factors of women, were randomly divided into misoprostol group and control group, 62 cases each. The misoprostol group received 400 μg of misoprostol immediately after delivery of the fetus. The control group received intramuscular oxytocin 20 IU (oxytocin) immediately after delivery. The duration of the third stage of labor, the amount of bleeding after 2 hours and the incidence of postpartum hemorrhage were observed in two groups. Results Compared with the two groups, the time of the third stage of labor in the misoprostol group was shortened by 4 minutes on average and that of the misoprostol group decreased by 137mL on average after 2 hours. The incidence of postpartum hemorrhage was lower than that of the control group by 17% on average (P <0.01). Conclusion Misoprostol has more contraction effect than oxytocin. Oral administration of 400ug can prevent postpartum hemorrhage caused by high risk factors.