论文部分内容阅读
人工流产胎儿标本２３例，孕龄１０～４１周，用免疫组织化学ＡＢＣ法，研究人胎儿脊髓神经肽Ｙ样神经元的发育和分布。结果在胎龄第１０周，发现脊髓后角浅层（ＲｅｘｔｄⅠ、Ⅱ层）已有神经肽Ｙ样免疫阳性神经元胞体存在，且阳性神经元总数随胎龄的增加而递增，并向后角深层（ＲｅｘｅｄⅢ～Ⅳ层）扩展神经肽Ｙ样阳性纤维，在胎龄第１０周，不仅出现于脊髓的灰质和白质，而且见于脊髓的被膜。随胎龄的增长，免疫阳性反应纤维相对集中于脊髓的植物性神经中枢的所在部位，揭示在妊娠早期，神经肽Ｙ可能与脊髓植物神经元的发育及其功能的调节有关。
Twenty-three cases of abortion fetus were collected and the gestational age was 10 to 41 weeks. The development and distribution of neuropeptide Y-like neurons in human fetal spinal cord were studied by immunohistochemical ABC method. Results At the 10th week of gestation, it was found that there were neuropeptide Y immunoreactive neuronal somatic cells in Rextd Ⅰ and Ⅱ layers, and the total number of positive neurons increased with the increase of gestational age, Deep (Rexed Ⅲ ~ Ⅳ) expansion of neuropeptide Y-like fibers in the 10th week gestational age, not only in the gray matter and white matter of the spinal cord, but also seen in the spinal cord capsule. With the increase of gestational age, the immunoreactive fiber is relatively concentrated in the site of the autonomic nerve center of the spinal cord, revealing that neuropeptide Y may be related to the development of spinal cord autonomic neurons and the regulation of their functions in early pregnancy.