卡氏肺孢菌肺炎(PCP)是一机体免疫系统缺陷时机会性感染所致疾病。严重联合免疫缺陷(SCID)小鼠缺乏有功能的CD4~+T细胞,卡氏肺孢菌感染后不出现肺炎症状,常用作研究PCP的动物模型。作者通过实验证实,此类感染小鼠肺部各种趋化因子在RNA表达水平上都没有统计学意义的升高。为阐明参与PCP的主要细胞和趋化因子在PCP Pneumocystis carinii pneumonia (PCP) is a disease caused by opportunistic infections in the body’s immune system. Severe combined immunodeficiency (SCID) mice lack functional CD4 ~ + T cells, pneumocystis carinii infection does not appear symptoms of pneumonia, often used to study the animal model of PCP. The authors confirmed by experiments that various chemokines in the lungs of such infected mice showed no statistically significant increase in RNA expression levels. To elucidate the major cells and chemokines involved in PCP in PCP