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本文实验结果表明,自制中药复方892号药液对移植性肺腺癌(LA一795)小鼠的脾细胞白细胞介素一2(IL_(-2))活性、肿瘤自然杀伤细胞(NKC)活性和血清肿瘤坏死因子(TNF)含量均有不同程度的提高作用。其中,IL_(-2)活性以892号药液小剂量组明显高于其它组;NKC活性以中西药联用组、892号药液大剂量组明显高于其它组;TNF含量以892号药液大、中、小剂量组明显高于其它组。中药组与西药组比较其差别有显著性意义(P<0.05或0.01)。提示892号药液可以提高荷癌小鼠的肿瘤免疫水平,为临床治疗肿瘤提供了重要的实验依据。
The results of this study indicate that IL- 2 activity and natural killer cell (NKC) activity of spleen cells in transplanted lung adenocarcinoma (LA-795) mice by self-made Chinese compound compound No. 892 solution And serum tumor necrosis factor (TNF) content have different degrees of improvement. Among them, the activity of IL_(-2) was significantly higher in the low-dose group of No. 892 than in the other groups; the activity of NKC in the combination of Chinese and Western medicines and the high-dose of No. 892 were significantly higher than those of other groups; the content of TNF was taken as No. 892 Liquor large, medium and small dose group was significantly higher than other groups. The difference between the Chinese medicine group and the Western medicine group was significant (P<0.05 or 0.01). It is suggested that the No. 892 drug solution can increase the tumor immune level of mice bearing cancer, and provides an important experimental basis for the clinical treatment of tumors.