全取代的呋喃酮[Ⅰ]易与胺类发生缩合反应,生成相应的插烯式酰胺,与甲胺在不同溶剂中可得单分子或双分子缩合产物。 这类缩合产物不能用碘甲烷,重氮甲烷甲基化;用过氧化氢氧化得到少一碳原子的二元酸;与乙酰乙酸乙酯作用生成吡啶衍生物;与格氏试剂作用,发生类似于α,β-不饱和羰基化合物的1,4-加成反应,生成产物业经合成方法证明。 The fully substituted furanones [I] are easily condensed with amines to form the corresponding amide of vinylidene, which can form mono- or bimolecular condensation products with methylamine in different solvents. Such condensation products can not be methyl iodide, diazomethane methylation; with hydrogen peroxide oxidation to a less carbon atoms of the dibasic acid; and ethyl acetoacetate generated pyridine derivatives; and Grignard reagents, a similar phenomenon occurred In α, β-unsaturated carbonyl compounds 1,4-addition reaction, the resulting product proved by synthetic methods.