鼻中隔穿孔修补一直是耳鼻喉科医生认为比较棘手的问题之一。目前对有症状的鼻中隔穿孔仍以手术修补为主,近年随着手术方法的改进,成功率不断提高,尤其是对大穿孔的修补也取得了较高的成功率。我们对鼻中隔穿孔的病因、临床表现,所采用的手术方式、以及术中所用移植物进行总结, Nasal septum perforation repair has been ENT physicians that one of the more difficult issues. Currently, symptomatic nasal septum perforation is still mainly surgical repair, with the improvement of surgical methods in recent years, the success rate continues to increase, especially for large perforation repair also achieved a high success rate. We summarize the causes of nasal septum perforation, clinical manifestations, surgical procedures used, and intraoperative graft,