【摘 要】
：
Pluripotent stem cells (PSCs) such as embryonic stem cells (ESCs),ESCs derlved by somatic cell nuclear transfer (ntESCs),and induced pluripotent stem cells (IPS
【机 构】
：
State Key Laboratory of Oncology in South China, Cancer Center, Collaborative Innovation Center for
论文部分内容阅读
Pluripotent stem cells (PSCs) such as embryonic stem cells (ESCs),ESCs derlved by somatic cell nuclear transfer (ntESCs),and induced pluripotent stem cells (IPSCs) have unlimited capacity for self-renewal and pluripotency and can give rise to all types of somatic cells.In order to maintain their self-renewal and pluripotency,PSCs need to preserve their telomere length and homeostasis.In recent years,increasing studies have shown that telomere reprogramming is essential for stem cell pluripotency maintenance and its induced pluripotency process.Telomere-associated proteins are not only required for telomere maintenance in both stem cells,their extra-telomeric functions have also been found to be critical as well.Here,we will discuss how telomeres and telomere-associated factors participate and regulate the maintenance of stem cell pluripotency.
其他文献
番茄是现今世界栽培十分广泛的蔬菜作物之一,随着人们对生活品质的要求不断提高,关于番茄品质性状的研究也越来越多。在番茄的众多品质性状中,可溶性糖含量有着重要的影响。
Just one day after the official announcement for the end of H1N1 influenza by WHO,Kumarasamy et al.(2010)reported the emergence of a new global health problem,w
It is my very great pleasure to announce the launch of Protein & Cell.Understanding the cell, the basic unit of life, is a complicated process but is the source
Understanding the world and then changing the world is an everlasting mission of the human being.Life is an important component and one of the most sophisticate
Pluripotent stem cells (PSCs) are capable of unlimited self-renewal in culture and differentiation into all functional cell types in the body,and thus hold grea
A recent study of chemotaxis revealed a new role for the proto-oncogene Ras in the social ameba Dictyostelium discoideum.Chemotaxis,the directional movement of
黄瓜（Cucumis sativus L.）是世界范围内广泛栽培的重要瓜类蔬菜，赤霉素是植物体中广泛存在植物激素，生物活性的赤霉素可以促进植株多方面的生长，并由一系列酶类催化合成，其中有3种
介绍了宁海县“两旱一水”发展的经过，分析了“两旱一水”的优点和问题，提出了今后的对策。