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1.6—二磷酸果糖(fructose—1,6—Diphosphate)简称FDP。它是一种具有调节机体糖代谢活性酶的作用,恢复及改善细胞分子水平代谢的药物。近年研究表明,本药是治疗心力衰竭、急性心肌梗塞、心绞痛、休克、心肌炎等疾病的良好的辅助药物,且相对无副作用。但临床应用上还有一定的局限性。本文就有关国内外文献综述如下。 一、药理作用 FDP作用于细胞膜,激活磷酸果糖激酶(PEK),加速糖酵解。其本身又可作为能量代谢的底
Fructose-1,6-diphosphate (FDP). It is a kind of medicine that has the function of regulating the activity of glucose metabolism enzyme in the body and restoring and improving the metabolism of cells and molecules. Recent studies show that the drug is a good adjunct to treat heart failure, acute myocardial infarction, angina, shock, myocarditis and other diseases, and relatively no side effects. However, there are some limitations in clinical application. This article on the domestic and international literature review is as follows. First, the pharmacological effects FDP role in the cell membrane, activate phosphofructokinase (PEK), accelerate glycolysis. It itself can be used as the end of energy metabolism