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廿碳五烯酸(EPA)是一种前列腺素(PG)先质脂肪酸,它在体内转变为三系PG 的同时,竞争性地抑制花生四烯酸(AA)代谢,从而使二系PG 合成减少。EPA 生成的三系PG 几乎没有促血小板聚集作用,但抑制血小板聚集的能力却和二系PG 相同,因而体内二系PG 减少和三系PG 增多可降低血小板聚集功能。EPA 还可降低血甘油三酯和胆固醇,降低血液粘滞度和增强红细胞膜的可塑性。因此,增加体内EPA 含量,有助于防治动脉粥样硬化和减少血管闭塞性疾病的发生。
Eicosapentaenoic acid (EPA), a prostaglandin (PG) precursor fatty acid, competitively inhibits arachidonic acid (AA) metabolism while converting to tertiary tetanus in vivo, thereby allowing the synthesis of two-line PG cut back. EPA generated three-line PG almost no platelet aggregation, but the ability to inhibit platelet aggregation is the same as the second-line PG, and thus reduce the second-line PG in vivo and three-line PG increased platelet aggregation can reduce the function. EPA can also lower blood triglycerides and cholesterol, lower blood viscosity and enhance the plasticity of the erythrocyte membrane. Therefore, increasing the body’s EPA content helps to prevent and treat atherosclerosis and reduce the occurrence of vascular occlusive disease.