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目的探讨超声指标——心肌机能指数(Tei)与血浆脑钠肽(BNP)水平鉴别收缩性心力衰竭(SHF)及舒张性心力衰竭(DHF)的临床应用价值。方法入选心力衰竭患者67例,按照左室射血分数(LVEF)分为SHF(LVEF<50%)及DHF组(LVEF≥50%)。32名健康者为对照组,测常规超声指标及Tei指数,并采用ELISA法测得血浆BNP水平。结果与对照组相比,DHF及SHF组Tei指数、BNP显著增高(P<0.01);心力衰竭两组相比,Tei指数、BNP在SHF组显著升高(0.63±0.11)比(0.82±0.20)ng/L,P<0.01;713.38ng/L比1345.86ng/L,P<0.05,且二者呈显著正相关(r=0.71,P<0.01)。结论Tei指数、BNP在心力衰竭患者显著升高,二者可鉴别SHF及DHF。
Objective To investigate the clinical value of using the ultrasonic index-Tei and BNP to differentiate between systolic heart failure (SHF) and diastolic heart failure (DHF). Methods Sixty-seven patients with heart failure were enrolled and divided into SHF (LVEF <50%) and DHF group (LVEF≥50%) according to left ventricular ejection fraction (LVEF). 32 healthy persons as the control group, routine ultrasonic indexes and Tei index, and the plasma BNP levels were measured by ELISA. Results Compared with the control group, the Tei index and BNP in DHF and SHF groups were significantly increased (P <0.01). The Tei index and BNP in SHF group were significantly higher (0.63 ± 0.11) than those in HF group (0.82 ± 0.20 ) ng / L, P <0.01; 713.38ng / L more than 1345.86ng / L, P <0.05, and there was a significant positive correlation between them (r = 0.71, P <0.01). Conclusion Tei index, BNP in patients with heart failure was significantly higher, the two can identify SHF and DHF.