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目的了解贵州省男性青年骨代谢生化标志物的特点及影响因素,为研究贵州省青少年生长发育提供参考资料。方法选取来自贵州省各地区426名18~20岁的男性青年,检测骨钙素(OC)、骨碱性磷酸酶(BAP)、血清钙磷水平及身高和体重。结果男青年OC,BAP及身高与体重呈正相关,高海拔地区与低海拔地区男性青年的各项测定指标差异无统计学意义;汉族男青年OC,BAP及身高,体重均高于少数民族,差异均有统计学意义(P值均<0.05)。家庭经济条件和父母文化程度对OC,BAP,身高和体重的影响具有统计学意义(P值均<0.05)。结论贵州地理海拔高度对男性青年骨形成生化标志物及主要形态指标的影响较小,种族遗传是主要影响因素,家庭经济条件和父母文化程度对男性青年骨形成生化标志物及身高体重有影响。
Objective To understand the characteristics and influencing factors of biochemical markers of bone metabolism in male youth in Guizhou Province and provide reference materials for the research on the growth and development of adolescents in Guizhou Province. Methods A total of 426 male adolescents aged 18 to 20 years from all regions of Guizhou Province were selected for determination of osteocalcin (OC), bone alkaline phosphatase (BAP), serum calcium and phosphorus levels, and height and weight. Results There was a positive correlation between OC, BAP and body height and body weight in male youth. There were no significant differences in the measurement indexes between male youth at high altitude and low altitude. The OC, BAP and height and weight of male youth were higher than ethnic minorities, All were statistically significant (P <0.05). Family economic conditions and educational level of parents have significant effect on OC, BAP, height and weight (P <0.05). Conclusion Guizhou geographical altitude has less influence on the biochemical markers of bone formation and major morphological indexes in young men, and ethnicity is the main influencing factor. The family economic conditions and parents’ educational level have an impact on the biochemical markers of bone formation and height and weight of male youth.