猪苓多糖是从植物猪苓〔Polyporus umbellatus (Pers.) Fr.〕的菌核中提取分离得到的一种葡聚糖。据文献报道,实验研究和临床观察证明,猪苓多糖具有提高机体免疫力,治疗慢性肝炎和抗肿瘤作用。为保证用药安全,制定药物质量标准,作者对其猪苓多糖的质量进行了比旋度测定,鉴别试验,分子量分布和特性粘数测定,含量测定方法的研究。实验部分一、比旋度测定精密称取本品适量,加水制成每毫升中含0.01g的溶液,测定其比旋度〔α〕_D~(25)为-5～15°(C=1,H_2O)。二、鉴别试验取本品0.02g加水2ml溶解,加95%乙醇6ml使沉淀,离心,取沉淀物置试管中,加水溶解后,α-萘酚试剂试验应成正反应;费林试剂(Fehling)试验,未水解者应 Polyporus umbellatus (Polysporum umbellatus (Pers.) Fr.) is a glucan extracted and isolated from the sclerotium of plant polyporus umbellatus (Pers.) Fr. According to reports in the literature, experimental studies and clinical observations have shown that Polyporus umbellatus polysaccharides have improved immunity, treatment of chronic hepatitis and anti-tumor effects. In order to ensure the safety of medications and formulate drug quality standards, the authors performed specific rotation measurement, identification tests, molecular weight distribution, intrinsic viscosity measurement, and content determination methods for the quality of Polyporus umbellatus polysaccharides. Experimental part I. Specific rotation is determined by accurately weighing the appropriate amount of the product, adding water to make a solution containing 0.01g per milliliter, and determining the specific rotation [α]_D~(25) is -5 to 15° (C=1) , H_2O). Second, the identification test to take this product 0.02g add water 2ml dissolved, plus 95% ethanol 6ml precipitation, centrifugation, take the precipitate was placed in a test tube, dissolved in water, the α-naphthol reagent test should be a positive reaction; Fering reagent (Fehling) test Unhydrolyzed