一些研究显示,唾液中的药物浓度常与血浆中浓度成比例,因而,在治疗监测或药物代谢动力学的研究中,唾液有可能用以代替血浆。唾液检测具有某些优点,例如:(1)能通过非创伤性技术收集唾液样本,多次收集对病人并无不适,亦无感染的危险;(2)某些药物在唾液中的 Some studies have shown that the concentration of drug in saliva is often proportional to the concentration in plasma and that saliva may be used instead of plasma in therapeutic monitoring or pharmacokinetic studies. Saliva testing has certain advantages, such as: (1) Saliva samples can be collected by noninvasive techniques and collected on multiple occasions without risk of infection and no infection; (2) Some drugs in saliva