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目的:从人格特征的角度探讨男男性行为者(men who have sex with men,MSM)艾滋病暴露前用药(pre-exposure pro-phylaxis,PrEP)使用意愿的影响因素。方法:选取卡氏16种人格因素量表中乐群性、敏感性、怀疑性和自律性4种因子分析MSM的人格特征以及不同人格特征者的用药意愿。结果:4种因子原始分与成年男性常模比较均有差异(P<0.000 1),其中乐群性和敏感性因子得分高于常模,怀疑性和自律性因子低于常模;单因素Logistic回归结果显示敏感性因子对用药意愿的影响明显,敏感性分数越高者用药意愿越强烈(OR=1.692),多因素Logistic回归结果显示敏感性分数越高者用药意愿越强烈(OR=1.359),其它因子对用药意愿的影响不大。结论:MSM人群的人格特征表现出与正常成年男性的不同之处,在PrEP的研究过程中需考虑到其人格特征的特殊性。
Objective: To investigate the influencing factors of the willingness of pre-exposure pro-phylaxis (PrEP) for men who have sex with men (MSM) from the perspective of personality traits. Methods: Four factors of music personality, sensitivity, suspicion and self-discipline were selected to analyze the personality traits of MSM and their willingness to use different personality traits. Results: There were significant differences between the natures of the four factors and the norm of adult male (P <0.000 1). The values of the music group and the sensitivity factor were higher than those of the norm and the factors of doubtful and self-discipline were lower than the norm. The single factor Logistic regression analysis showed that the sensitivity factor had a significant effect on the medication willingness. The higher the sensitivity score was, the stronger the drug willingness was (OR = 1.692). The multivariate Logistic regression showed that the higher the sensitivity score was, the stronger the medication preference was (OR = 1.359 ), Other factors have little effect on medication intent. CONCLUSIONS: The personality traits of MSM population are different from that of normal adult men. In the process of PrEP research, the particularity of personality traits should be taken into account.