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分析了32例葡萄胎患者化疗前后血清中SIL－2R和TNF含量的变化。结果表明:化疗前血清中SlL－2R和TNF含量均显著地高于正常对照组（P＜0.01，P＜0.001），化疗后均有明显的下降（P＜0.05），SIL－2R和TNF与β－HCG呈正相关（r=0.6263，r＝0.6105，P＜0.01）。机理不明。结果提示：血清SIL－2R和TNF可作为葡萄胎患者免疫功能监测指标之一，并可作为疗效判断的参考。
The changes of serum SIL-2R and TNF levels in 32 patients with hydatidiform mole before and after chemotherapy were analyzed. The results showed that the content of SlL-2R and TNF in serum before chemotherapy was significantly higher than that in normal control group (P<0.01, P<0.001), and there was a significant decrease after chemotherapy (P<0.05). SIL-2R and TNF were associated with There was a positive correlation between β-HCG (r=0.6263, r=0.6105, P<0.01). The mechanism is unknown. The results suggest that serum SIL-2R and TNF can be used as a monitoring index of immune function in patients with hydatidiform mole, and can be used as a reference for the evaluation of therapeutic effect.