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用垂体后叶素 (VP)和善得定治疗肝硬化食管曲张静脉破裂出血 ,对比观察两药的疗效。结果 :善得定和VP两药 72小时内止血率分别为 75 .0 %、76.4% ,一周内再出血率分别为 2 2 .2 %、2 3 .6% ,两药比较无显著差异。VP副作用达2 7.8% ,善得定副作用较轻微占 8.3 % ;两组间肝性脑病发生率无显著性差异。结论 :对经济困难的食管曲张静脉破裂出血患者如无VP应用禁忌证仍可为首选 ,善得定可作为有VP禁忌证或效果不佳时的用药。
The use of pituitrin (VP) and good for the treatment of cirrhosis of esophageal variceal bleeding, comparative observation of the efficacy of the two drugs. Results: The hemostatic rates of Sertraline and VP in 72 hours were 75.0% and 76.4%, respectively. The rates of rebleeding within one week were 22.2% and 23.6% respectively. There was no significant difference between the two drugs. VP side effects of up to 2 7.8%, good set of side effects accounted for 8.3% slightly; between the two groups no significant difference in the incidence of hepatic encephalopathy. CONCLUSIONS: In patients with difficult-to-treat esophageal variceal bleeding who are contraindicated without VP, contraindication may still be the first choice, and Sedatives may be considered as a contraindication or ineffective.