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目的：研究心脏收缩调节器( CCM)对终末期扩张型心肌病患者左心功能影响。方法2例终末期扩张型心肌病患者,在接受了最佳药物治疗,其中1例伴完全性左束支传导阻滞( CLBBB)者接受了再同步化治疗,另1例窄QRS波者接受了埋藏式心脏转复除颤器治疗,仍然反复发作心力衰竭,在原植入器械的对侧植入CCM系统,包括了3根电极,1根右房电极,另外2根为右心室电极植入室间隔部位,这2根电极之间,以及与原右室导线之间间隔2 cm以上。根据导线的位置及参数决定导线与起搏器联接顺序,术后随访1个月。结果 CCM能改善术后即刻及术后短期的心脏功能。结论对接受最佳药物治疗仍有反复心力衰竭发作的终末期心肌病患者,不管是否存在CLBBB或接受心脏再同步化治疗,仍能够从CCM治疗中获益。“,”Objective To study the efficacy in patients with chronic heart failure treated with cardiac contractility mod-ulation( CCM) . Methods Two heart failure patients with symptomatic heart failure and reduced left ventricular ejection fraction, sinus rhythm were chosen. One patient already implanted CRTD was considered CRT non-responders and another with narrow QRS had been implanted ICD. the CCM device were successfully implanted under local anesthesia at the con-tralateral infraclavicula. Two right ventricular septal pacing leads were placed in the right ventricular septum as far as possible with the original right ventricular defibrillation lead(≥2 cm) . An atrial lead was fixed in the right atrium. Results CCM was able to improve left ventricular systolic function both immediate postoperation and short-term follow-up. Conclusion Patients with end-stage cardiomyopathy, whether with complete left bundle branch block or accepted CRT treatment, can still benefit from CCM treatment.