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多凝集红细胞抗原是一组不符合免疫学规律,没有特定的抗体反应、呈多凝集现象的一组红细胞。根据Bird的定义:“与血型无关,与所有血清抗体都反应”。最早是在1930年Thomsen和Friendrich发现这一现象。多凝集红细胞是因为各种原因而产生的膜抗原暴露,从而产生的“多凝集”现象,这与临床疾病相关、与人体免疫机制相关,与红细胞免疫相关。
Multi-agglutinating erythrocyte antigen is a set of non-compliance with immunological laws, there is no specific antibody response was showed a more agglutination phenomenon of red blood cells. According to Bird’s definition: “Has nothing to do with blood type, and all serum antibody reaction ”. It was first discovered by Thomsen and Friendrich in 1930. Multi-agglutination of red blood cells is due to a variety of reasons the membrane antigen exposure, resulting in “more agglutination ” phenomenon, which is associated with clinical disease, and human immune mechanisms, and red blood cell immune related.