In order to systemically summarize and integrate technology of highway construction in permafrost regions on the Qinghai-Tibet Plateau,we studied disciplines and mechanisms of formation and development of problems and challenges in highway engineer-ing in high-altitude permafrost regions based on construction experiences for 50 years and on 30 years of research regarding the Qinghai-Tibet and Xikang highways.Embankments,pavements,bridges,and countermeasures for ecosystem protection in per-mafrost regions were the main study objects.We combined extensive analysis of key problems of engineering stability with inter-action between permafrost and highways,theoretical models,indoor tests,and field tests to reveal the interaction between em-bankments,pavements,bridge piles,and permafrost.In this paper,we propose a series of engineering measures for highway sta-bility,design parameters,key indexes for pavement durability in low temperature,relationships between re-freezing time of bridge-pile foundation and strength development as well as ecosystem recovery in high-latitude cold regions;these eventually form a construction technology package for permafrost regions. In order to systemically summarize and integrate technology of highway construction in permafrost regions on the Qinghai-Tibet Plateau, we studied disciplines and mechanisms of formation and development of problems and challenges in highway engineer-ing in high-altitude permafrost regions based on construction experiences for 50 years and on 30 years of research regarding the Qinghai-Tibet and Xikang highways. Embankments, pavements, bridges, and countermeasures for ecosystem protection in per-mafrost regions were the main study objects. We combined extensive analysis of key problems of engineering stability with inter-action between permafrost and highways, theoretical models, indoor tests, and field tests to reveal the interaction between em-bankments, pavements, bridge piles, and permafrost. In this paper, we propose a series of engineering measures for highway sta- bility , design parameters, key indexes for pavement durability in low temperature, relationships between re-freezing time of bridge-pile foundation and strength development as well as ecosystem recovery in high-latitude cold regions; these eventually form a construction technology package for permafrost regions.