肿瘤转移是一个相当复杂的过程,涉及肿瘤细胞、血管内皮细胞与细胞外基质(extracellularmatrix,ECM)的相互作用和血小板瘤栓的形成。现已明确,细胞与ECM的作用是由于细胞表面的整合素等分子能特异地识别ECM分子的某些氨基酸序列,并与之结合;血小板表面存在大量bβ3整合素... Tumor metastasis is a rather complex process involving the interaction of tumor cells, vascular endothelial cells with the extracellular matrix (ECM) and the formation of thrombocytopenia. It has been clear that the role of cells and ECM is due to cell surface integrin and other molecules can specifically identify some of the amino acid sequences of ECM molecules and combined with the platelet surface there is a large number of bβ3 integrin ...