猕猴桃果汁对染铅小鼠驱铅效果观察

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为观察猕猴桃果汁对染铅小鼠体内铅含量的影响 ,选用 6 0只 18~ 2 2g体重的昆明种雄性小鼠分为 3个试验组、1个模型对照组和 1个空白对照组进行实验观察。低、中、高剂量组和模型对照组小鼠自由饮用Pb2 + 浓度为 5 46 2mg L的水溶液 ,低、中、高剂量样品组分别灌胃给予 10 0、2 0 0、4 0 0ml kgBW 剂量的受试液 ,模型对照组灌胃去离子水 ,空白对照组饮用、灌胃去离子水。实验期间记录饮用水量 ,连续 30d后 ,采血 ,取肝、股骨 ,用原子吸收分光光度法测定铅含量。结果发现 ,染铅各组铅摄入剂量相当 ,3个试验组小鼠全血铅和肝组织铅水平显著低于模型对照组 ,各剂量对小鼠股骨铅含量无明显影响。提示猕猴桃果汁具有促进排铅作用。 To observe the effect of kiwifruit juice on the lead content in lead-exposed mice, 60 male Kunming mice weighing 18 ~ 22 g were divided into three groups: one experimental group, one model control group and one blank control group Observed. Low, medium and high dose groups and model control group mice were free to drink Pb2 + concentration of 5 462mg L aqueous solution, low, medium and high dose groups were given gavage 10 0,2 0 0,4 0 0ml kgBW dose Of the test solution, model control group gavage deionized water, blank control group drinking, gavage deionized water. Record the amount of drinking water during the experiment, after 30 consecutive days, blood, liver and femur were taken for determination of lead content by atomic absorption spectrophotometry. The results showed that the lead intake of each lead-in group was similar, and the levels of lead in the whole blood and the liver of the three experimental groups were significantly lower than those of the model control group. There was no significant effect of each dose on the femoral lead content. Tips Kiwifruit juice has the role of promoting lead.
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