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将1168例≤80岁拟行直肠癌切除患者随机分组。术前放疗加手术治疗组照射5次/周,共25Gy后1周内行手术,另一组为单独手术组。剔除不适合条件者,术前放疗组局部复发率显著低于单独手术组,前者为11%(63/553),后者为27%(150/557),P<0.001。随访5年,术前放疗组5年生存率为58%,单独手术组为48%(P=0.004)。肿瘤切缘无肿瘤,为有效局部切除,有效
1168 patients with ≤80-year-old scheduled resection of rectal cancer were randomly divided into groups. The preoperative radiotherapy plus surgery group was irradiated 5 times per week. A total of 25 Gy was performed within 1 week after surgery. The other group was operated alone. Excluding unsuitable conditions, the local recurrence rate in the preoperative radiotherapy group was significantly lower than in the surgery alone group, with the former being 11% (63/553) and the latter being 27% (150/557), P<0.001. After 5 years of follow-up, the 5-year survival rate was 58% in the preoperative radiotherapy group and 48% in the single surgery group (P=0.004). Tumor margin without tumor, effective for local resection, effective