目前约有70%的肿瘤需要进行放射治疗,但大多数肿瘤都存在一定的放射抗拒性,即便在精确放疗占主导地位的今天,临床上放疗野内复发的情况依旧存在。因此放射增敏剂成为了近年来的研究热点,而放射增敏机制的研究因其能为增敏剂的临床应用和新药的研制和开发提供理论依据而备受关注 At present, about 70% of the tumors require radiotherapy, but most tumors have some radioresistance. Even in the days when the exact radiotherapy predominates, the recurrence of clinical radiotherapy in the field still exists. Therefore, radiosensitizer has become a research hotspot in recent years, and the research on the mechanism of radiosensitization has drawn much attention because of its potential application as a theoretical basis for the clinical application of sensitizers and the research and development of new drugs