Aspoxicillin(ASPC)系日本田边制药公司开发的注射用青霉素制剂.化学结构的特点是在青霉素母核的6位侧链上引入N~4-甲基-D-天冬酰胺.另外,侧链上除苯甘氨酸外,还引入了氨基酸,从而改善了药物在生物体内动态.本药在青霉素制剂方面还是首创,被称之为“氨基酸型青霉素”(图1). Aspoxicillin (ASPC) is an injectable penicillin preparation developed by Japan’s Tanabe Pharmaceutical Co. Ltd. The chemical structure is characterized by the introduction of N-4-methyl-D-asparagine onto the 6-side penicillin nucleus, and the side chain In addition to phenylglycine, but also the introduction of amino acids, thereby improving the dynamics of the drug in the body. The drug penicillin preparations is still the first, known as “amino acid type penicillin ” (Figure 1).