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目的观察A型肉毒毒素(BTXA)治疗偏侧面肌痉挛及眼睑痉挛的疗效。方法用A型肉毒毒素对70例偏侧面肌痉挛及12例眼睑痉挛患者行面部肌肉局部多点注射,分析其治疗效果。结果 70例偏侧面肌痉挛者,完全缓解25例(35.7%),明显缓解45例(64.3%);12例眼睑痉挛患者,完全缓解4例(33.3%),明显缓解7例(58.3%),无效1例(8.4%)。结论 A型肉毒毒素局部肌肉注射可有效控制局部肌张力过高,缓解局部肌肉痉挛,是简便、安全的治疗方法 。
Objective To observe the efficacy of botulinum toxin type A (BTXA) in the treatment of hemifacial spasm and blepharospasm. Methods A total of 70 patients with hemifacial spasm and 12 patients with blepharospasm were injected with botulinum neurotoxin type A locally to investigate the therapeutic effect. Results In 70 patients with hemifacial spasm, complete remission was achieved in 25 cases (35.7%) and in 45 cases (64.3%). In 12 patients with blepharospasm, complete remission was achieved in 4 cases (33.3%) and in 7 cases (58.3% , 1 invalid (8.4%). Conclusion Local intramuscular injection of botulinum toxin type A can effectively control local hypertonia and relieve local muscle spasms, which is a simple and safe treatment.