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本文报告84例口腔鳞癌行计划性金属铂诱导化疗后的病理形态学分析的资料.参照放疗后的组织病理学评价标准,观察原发灶炎性细胞浸润、癌巢坏死崩解和纤维组织增生,按0~Ⅳ级共5级标准评定(0~Ⅰ级为化疗病理无效,Ⅱ~Ⅳ级为有效),结果显示:0~Ⅳ级分别为12、4、18、39和11例;和临床疗效结果相似.本研究认为:金属铂诱导化疗既与临床疗效有关,亦是肿瘤临床消退的病理形态基础,应该对口腔鳞癌的近、远期疗效产生重要影响.
This paper reports 84 cases of oral squamous cell carcinoma of the scheduled metal platinum chemotherapy after histopathological analysis of the data. According to the histopathological evaluation criteria after radiotherapy, inflammatory cell infiltration, disintegration of cancerous nests and fibrous tissue hyperplasia were observed. According to 0 ~ ~ Ⅳ grade is valid), the results showed: 0 ~ Ⅳ grade were 12,4,18,39 and 11 cases; and clinical efficacy of similar results. This study suggests that: platinum induction chemotherapy is not only related to clinical efficacy, but also the pathological basis of clinical regression of the tumor, oral and squamous cell carcinoma should have near and long-term effect have a significant impact.