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糖尿病患者周围血管闭塞性动脉病变的危险性以及问歇性跛行症、坏疽和截肢的发病率高,与许多因素有关,其病程和原因还不甚明确。作者对 Mayo 医院年龄在50～70岁的583例患者和124名正常人进行了长达5年的随访研究,旨在评定糖尿病与闭塞性周围动脉病变的关系。将受试者分为以下4组:①正常对照组(NC)124人;②无糖尿病的闭塞性动脉疾病组(ASO)157人;③单纯糖尿病而无闭塞性动脉病变组(DM)295人;④糖尿病伴有闭塞性动脉病变组(DM+ASO)131人。对每1例均进行病史采集与体格检查。股动脉、腘动脉或胫后动脉脉搏减弱或消失、有间歇性跛行症或股动脉杂音者,诊断为闭塞性动脉病变。有典型足部感觉迟钝或膝反射显著减弱者表明糖尿病性神经病变。冠心病的诊断依据运动后胸
The risk of vascular occlusive arterial disease around diabetic patients and the high incidence of intermittent claudication, gangrene and amputation are related to many factors and their duration and causes are not well understood. The authors conducted a five-year follow-up study of 583 patients and 124 normal individuals aged 50-70 in Mayo Hospital to assess the relationship between diabetes and peripheral arterial occlusive disease. Subjects were divided into the following 4 groups: ① normal control group (NC) 124; ② non-diabetic group of occlusive arterial disease (ASO) 157; ③ simple diabetes and non-occlusive arterial disease group (DM) 295 ; ④ Diabetic patients with arterial occlusive disease (DM + ASO) 131. For each case were collected history and physical examination. The femoral artery, popliteal artery or posterior tibial artery pulse weakened or disappeared, intermittent claudication or femoral artery noise, diagnosis of occlusive arterial disease. Patients with typical foot sensation or a significant decrease in knee reflexes indicate diabetic neuropathy. Coronary heart disease diagnosis based on chest exercise