本文概述了牙密螺旋体(Td)与成年人牙周炎的关系及其生物学性状、致病物质及致病机理等方面的主要研究成果。表明Td栖息于龈下菌斑中,通过酸性粘多糖粘附于牙周上皮组织,并能产生一系列的破坏性的酶和淋巴细胞增殖抑制因子等破坏牙周组织,因而它是牙周病的重要致病因子之一。 This article summarizes the relationship between Treponema Pallidum (Td) and adult periodontitis and its main research results on its biological properties, pathogenic substances and pathogenesis. Td perches in subglottic plaque, adhesion through the acid mucopolysaccharide in periodontal epithelial tissue, and can produce a series of destructive enzymes and lymphocyte proliferation inhibitory factor and other damage to periodontal tissue, it is a periodontal disease One of the important virulence factors.