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作者对145例流行性出血热患者行尿沉渣细胞及有形成份(USCTC/HP)、24小时尿蛋白(24huPro)、尿血肌酐比值(u/sCr)、尿β_2-微球蛋白(uβ_2-MG)、肾衰指数(RFI)、滤过钠排泄分数(FE N_a)、尿N-乙酰-β-D-氨基葡萄糖苷酶(尿NAG)等12项肾功能指标的检测.结果表明:多项肾功能指标在本病各期、各型中均各具有规律性,其升降幅度同病情轻重和肾衰程度密切相关.其中USCTC,24huPro,u/sCr,uβ_2-MG等4项于肾衰早期即有显著变化,可视为早期肾衰诊断的预警性指标;前3项和RFI,FE_(Na)等5项为判断肾衰程度的敏感指标;24huPro,u/sCr和尿NAG可作为本病恢复期肾功能监测和随访指标。
In this study, 145 patients with epidemic hemorrhagic fever were enrolled in this study. USCTC / HP, 24huPro, u / sCr and uβ_2-MG were measured in patients with epidemic hemorrhagic fever, , Renal failure index (RFI), filtration sodium excretion fraction (FE N_a), urinary N-acetyl-β-D-glucosaminidase (urinary NAG) were measured.The results showed that: Function index in each stage of the disease, each type has its own regularity, the extent of its decline with severity and severity of renal failure is closely related to which USCTC, 24huPro, u / sCr, uβ_2-MG and other 4 in the early renal failure that There are significant changes can be regarded as early warning indicators of early diagnosis of renal failure; the first three and RFI, FE_ (Na) and other five indicators to determine the sensitivity of renal failure; 24huPro, u / sCr and urine NAG can be used as the disease Convalescent renal function monitoring and follow-up indicators.