目前,已经确定某些传染性和免疫缺陷性疾病与人的 HLA-D/DR 区基因(HLA-DR 抗原)密切相关,具有很重要的临床和预测价值。在遭受鼠疫流行和大流行的人群中所进行的血型基因浓度改变的回顾性免疫遗传学分析表明,多数情况下具有较大的相关性。为了在进化成熟的能引起多形性基因系统平衡紊乱的寄生系中建立动物流行病过程的实验模型,我们分别将128和131只大沙土 Currently, it has been established that certain infectious and immunodeficiency diseases are closely related to human HLA-DR / DR gene (HLA-DR antigen) and have important clinical and predictive value. Retrospective immunogenetic analysis of changes in blood group gene concentrations in populations exposed to the plague and pandemic showed a large correlation in most cases. In order to establish an experimental model of zoonotic processes in a well-developed parasitic lineage that causes polymorphism in the pleiotropic gene system, 128 and 131 large sand