目的探究丁苯酞治疗急性脑梗死的临床疗效及其对血液流变学的影响。方法 60急性脑梗死患者,随机分为试验组和对照组,每组30例,两组患者均给予抗血小板、改善血循环、补充神经营养等药物治疗,此外,对照组患者采用维生素E胶囊口服治疗,试验组采用丁苯酞软胶囊口服治疗。观察两组临床疗效。结果试验组的治疗总有效率为93.3%,显著优于对照组的76.7%,两组比较差异具有统计学意义(P<0.05);同时,试验组患者的血液流变学各项指标均显著优于对照组患者,比较差异具有统计学意义(P<0.05)。结论丁苯酞能够有效改善急性脑梗死患者的血液流变学指标,提高治疗有效率,值得在临床中推广应用。 Objective To investigate the clinical efficacy of butylphthalide in the treatment of acute cerebral infarction and its effect on hemorheology. Methods 60 acute cerebral infarction patients were randomly divided into experimental group and control group, 30 cases in each group. Both groups were given antiplatelet, blood circulation and neurotrophic drugs. In addition, patients in the control group were treated with vitamin E capsules orally , The experimental group using butylphthalide soft capsule oral treatment. The clinical effects of two groups were observed. Results The total effective rate of the experimental group was 93.3%, which was significantly better than that of the control group (76.7%), the difference between the two groups was statistically significant (P <0.05); meanwhile, the indexes of hemorheology in the experimental group were significant Compared with the control group, the difference was statistically significant (P <0.05). Conclusion Butylphthalide can effectively improve the hemorheological parameters of patients with acute cerebral infarction and improve the treatment efficiency, which is worth popularizing in clinic.