猩红热在国内原为华北和长江流域较为常见的传染病,南方各省较为少见。我省地处亚热带,长期以来均未见此病流行之记载,偶有少数散发病例或疑似病例的疫情报告,亦并无病原学的证实。1973年春福州市不断出现临床上酷似猩红热的病人,并破季在6—7月间出现了较大的流行,发病率高达107.1/10万,出现了有史以来的新纪录。为了查明病原,澄清疫情,在福州市有关医疗卫生单位密切配合下,对部份发病较严重的街道与单位进行了有关流行病学的调查和病原菌的分离与血清学鉴定,结果确定了此次是一次乙型 A 群链球菌所引起的猩红热流行。现将若干问题的调查结果整理如下。 Scarlet fever in the country was originally a common infectious disease in North China and the Yangtze River basin, the southern provinces are relatively rare. The province is located in the subtropical zone, has long been a record of the epidemic of the disease, occasional few cases of dissemination or suspected cases of the outbreak report, there is no etiology confirmed. In the spring of 1973, there was a continuous epidemic of patients with scarlet fever clinically in Fuzhou City, and the breaking season witnessed a large epidemic between June and July with a morbidity rate of 107.1 / 100,000 and a new historical record. In order to identify the pathogen, to clarify the outbreak, in Fuzhou City, in close cooperation with the medical and health units, some of the more serious street and unit were conducted epidemiological investigation and isolation of pathogenic bacteria and serological identification, the results confirmed this The second is a group A streptococcus caused by the scarlet fever. The findings of several questions are summarized below.