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目的:探讨分析甲型H1N1流行性感冒裂解疫苗的安全性。方法:通过主动监测点的设立以及中国免疫规划监测信息管理系统对本地被动监测收集接种甲型H1N1流行性感冒裂解疫苗免疫接种后不良事件(AEFI)报告中的个案数据进行流行病学分析。结果:免疫接种后不良事件AEFI报告总发生率为36.3/10万,不良反应发生率为28.51/10万。结论:甲型H1N1流行性感冒裂解疫苗在接种后主要为一般反应,异常反应的发生率较低,具有较高的安全性,在临床上值得推广。
Objective: To investigate the safety of influenza A H1N1 influenza vaccine. Methods: The epidemiological analysis of case data from passive surveillance (AEFI) of vaccinated influenza A (H1N1) vaccination in local areas was conducted through the establishment of an active surveillance site and the China National Immunization Program Monitoring Information Management System. Results: The total incidence of AEFI after immunization was 36.3 / 100 000 and the incidence of adverse reactions was 28.51 / 100 000. Conclusion: Influenza A H1N1 influenza lysis vaccine after vaccination mainly for the general reaction, the incidence of abnormal response is low, with high safety, it is worth to promote in the clinic.